Systemic Lupus Erythematosus ( Sle ) - 1591 Words

Systemic Lupus Erythematosus Systemic lupus erythematosus (SLE) is an autoimmune disease that affects multiple tissues and systems and with significant variable clinical features and organ involvement (Cava, 2010). It is characterized by a chronic, relapsing, inflammatory and often febrile multisystemic disorder of connective tissue with wide spectrum of involvement of skin, joints, kidneys and serosal membranes. The exact etiology is noknown, but it represents failure of the regulatory mechanisms of immune system in which body s own defenses are turned against themselves (Edworthy, 2005##########). It has a worldwide distribution with unpredictable course of flares and remissions, where a cumulative damage over time significantly†¦show more content†¦The disease is milder and survival is higher among persons with isolated cutaneous and musculoskeletal disease than in those with renal and CNS involvement. the most frequent causes of death in SLE patients are Infections and diseases of the cardiovascular, renal, pulmonary, and central nervous systems (Bartels et al., 2012). In spite of the improvement of the survival rate, patients with SLE still have a higher death rate (3-5 times) than that of general population (Schur, 2001). B. Etiology: The definite pathologic mechanisms of SLE remain elusive, and the etiology of SLE is known to be multi-factorial, involving genetic, hormonal, and environmental factors. Environmental triggers with susceptible genetic background, act on the immune system to initiate autoimmunity (Tiffin et al., 2013). 1- Genetic factors: There is a clear genetic component in SLE, with a sibling risk ratio 8- 29 folds higher than that in the general population and a 10 folds increase in disease concordance in identical twins. In addition, there is a 24-56% concordance rate in monozygotic twins, compared with a 2-5% risk in dizygotic twins (Deng and Tsao, 2010). Many genes that may contribute to lupus have been identified by means of whole-genome scans from families in whom multiple members have SLE (Namjou et al., 2007). The genes associatedShow MoreRelatedSystemic Lupus Erythematosus ( Sle )1689 Words   |  7 Pagesare threatening to the mankind. Systemic lupus erythematosus (SLE) is a classic example of such a disease. SLE is a chronic, often life-long, autoimmune condition, ranging from mild to severe in severity. SLE may affect many organs in the body, including but not limited to kidneys, skin, joints, respiratory and nervous systems. The name of this disease describes it; word systemic indicates the widespread involvement of various tissues and organs of the body. Lupus is a word derived from Latin languageRead MoreSystemic Lupus Erythematosus ( Sle ) As Simply Lupus1604 Words   |  7 PagesAbstract Most know Systemic Lupus Erythematosus (SLE) as simply lupus. It is difficult to diagnose and treat but the symptoms can be mentally and physically devastating for any patient. Many may not realize the extent to which a person with SLE is affected on a day to day basis. It is important for healthcare professionals to understand the disease process, including the cause, signs, symptoms, and treatment of SLE. By understanding the aforementioned, healthcare professionals can assist with reportingRead MoreSystemic Lupus Erythematosus ( Sle )1780 Words   |  8 Pages(LN) Systemic lupus erythematosus (SLE) is a chronic inflammatory disease, immune-complex-mediated multi-systemic autoimmune condition of multifactorial etiology (Mak and Tay 2014). LN is an inflammatory condition affecting the kidneys which is caused by SLE, an autoimmune disease that is more common among women. About half of all people with SLE develop lupus nephritis, and of these about 1/10 experience chronic kidney disease or kidney failure (Henderson et al. 2012). Epidemiology of Lupus nephritis:Read MoreSystemic Lupus Erythematosus And Its Effects On The Body s Own Immune System2633 Words   |  11 Pages Systemic Lupus Erythematosus, or Erythematous, also known as SLE, is a chronic inflammatory, autoimmune disease that transpires when the body’s own immune system assaults, with â€Å"variable manifestations†, it’s own tissues and organ systems throughout the itself1,2,3. This can also include joints, heart, lungs, skin, brain, blood cells, etc1. Systemic Lupus Erythematosus is known to have an impact on the organ network involved with immune complexes and multiple antibodies, especially antinuclearRead MoreLupus : An Autoimmune Disease3344 Words   |  14 PagesWhat is Lupus? Lupus is an autoimmune disease in which our autoantibodies target self-proteins, known as ANAs. Systemic Lupus Erythematosus (SLE) is understood to be caused by our genetics and the environmental triggers from our everyday lives. There are four different types to this incurable but manageable disease, Cutaneous Lupus Erythematosus, Drug-induced Lupus Erythematosus, Neonatal Lupus, and Systemic Lupus Erythematosus. I will cover all of them, the main focus is on Systemic Lupus ErythematosusRead MoreSystemic Lupus Erythmatosus Essay example1364 Words   |  6 PagesLupus is a chronic inflammatory disease that occurs when your body’s immune system attacks your own tissues and organs. The inflammation caused by lupus can affect many body systems including the following: joints, skin, kidneys, blood cells, heart and lungs. Lupus occurs more frequently in women than in men. There are four different types of Lupus that exist. They are Systemic lupus erythematosus, Discoid lupus erythematosus, Drug-induced erythematosus, and Neonatal lupus. The most common andRead MoreThe Pathogenesis Associated With Sle2382 Words   |  10 Pagesassociated with SLE is complex and attributed to various factors. These factors include sex, the imbalance of hormones, and ones’ hypothalamus, pituitary, and adrenal axes. Others have said that it is attributed to the cells in your body that are dying, over active help of the T cells in the body, defective B cells, and the shifting of the T helper 1(Th1) to T helper 2 (Th2), which are responsible for the B cells causing   them to produce these pathogenic antibodies that cause SLE. (Cambridge, TeodorescuRead MoreSymptoms And Treatment Of Systemic Lupus Erythematosus1183 Words   |  5 PagesPSYCHOSIS IN SYSTEMIC LUPUS ERYTHEMATOSUS: A REVIEW Abstract Key words – Lupus, Psychosis, SLE, NP SLE, steroids, reversible INTRODUCTION Systemic lupus erythematosus (SLE) is a chronic inflammatory and autoimmune disease of multifactorial etiology that can affect many organs and systems (Sato, 2002). The studies show a higher prevalence in women (approximately 90% of cases), especially during childbearing years, i.e. between 15 and 45 years of age; more common in women of black ethnicity thanRead More Systemic Lupus Essay1613 Words   |  7 Pages Systemic lupus erythematosus (SLE) is a fairly common disease identified as episodes of inflammation and damage to joints, tendons, and various organs. The most effected organs are the heart, lungs, brain, kidneys, blood vessels, and skin. Lupus affects each individual differently and the effects could be mild to severe depending on the individual. SLE is an autoimmune disease where the body’s immune system attacks the healthy cells and tissues in the body (Ohio State, 2009). The main cause ofRead MoreClinical Pathology : Systemic Lupus Erythematosus8402 Words   |  34 PagesZagazig University Faculty of Medicine Clinical Pathology Department Association of STAT4 Gene Single-nucleotide Polymorphism with Systemic Lupus Erythematosus Thesis Submitted for partial fulfillment of M.D. degree in clinical pathology By Marwa Abd El-Monem Mohamed Ateya MB.B.CH. Ass .lecturer of Clinical Pathology Faculty of Medicine Zagazig University Prof. Dr. Lamiaa Abd Al-wahab Mohammad Professor of Clinical Pathology Faculty of Medicine Zagazig University Prof. Dr. Asmaa

Annotated Bibliography On Video Surveillance - 3355 Words

ABSTRACT The importance of Video Surveillance is increasing significantly everyday as organizations seek to safe guard their physical, information and capital assets. With the same vigour, the necessity to observe large number of people on roads, tourist spots, traffic lights, etc. is increasing to seek and pull more and more useful information. These demands calls for Smart Video Surveillance, analogous to traditional analog human-force-consuming approaches. This report is focussed to study such various technologies and ideas for implementation in Video Surveillance System. A lot of human resources is used for tracking and surveillance. The effort for this report is guided for occlusion, tracking mechanism, camera shift and spacio-temporal. All these techniques can be implemented for different usages. Table of Contents: 1. Introduction†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦1 1.1 Motivation†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦1 1.2 Background†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..2 2. Techniques used to solve Partial Occlusion in Face Recognition Systems†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦3 2.1 Face Recognition by Support Vector†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦3 2.2 Improving the Recognition of Faces Occluded by Facial Accessories†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.4 2.2.1 Approach†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.........................4 2.2.2 Occlusion Detection†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦5 3. Technique for video analysis of crowded scenario†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..7 3.1 Pre-processing†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦9 3.2 VideoShow MoreRelatedAnnotated Bibliography: Issue of IT Ethics2194 Words   |  9 PagesAnnotated Bibliography Over the last several years, the issue of IT ethics has been increasingly brought to the forefront. This is because of transformations occurring through rapid advancements and the way various applications are utilized. To fully understand what is taking place requires conducting an annotated bibliography on the subject and the impact it is having on these standards. These findings will highlight the overall scope of the challenges and the long term effects they are havingRead MoreAnnotated Bibliography: Security and Crime in Cyberspace3308 Words   |  13 PagesAnnotated Bibliography Over the last several years, the issue of IT ethics has been increasingly brought to the forefront. This is because of transformations occurring through rapid advancements and the way various applications are utilized. To fully understand what is taking place requires conducting an annotated bibliography on the subject and the impact it is having on these standards. These findings will highlight the overall scope of the challenges and the long term effects they are havingRead MoreLyme Disease Public Education Plan2465 Words   |  10 PagesLyme Disease Public Education Plan Table of Contents Objective 2 Fact Sheet 2-6 Data Sheet 6-8 Cause and Effect Sheet 8 Disease Analysis Sheet 9-11 Disease Control Plan 11 References 13 Annotated bibliography 14 Objective: Lyme disease can be a very serious disease if not treated early enough. The most important way to keep from getting the disease is prevention. Education is the key to prevention. The only way to contract the disease is to be bitten by a tick that isRead MoreThe Classroom Discussion Model of Teaching (*Arends, 2001)6735 Words   |  27 Pagesunit of study utilizing the models studied during the semester.I have also taught the models to classes of undergraduates who do not have their own classrooms in which to practice using the models. The process is very similar except that students are video taped at special sessions between classes teaching a lesson which they have planned. The tapes are then reviewed with the students.Summary of the steps used in teaching the models to student teachers-in-training who do not have an actual classroomRead MoreContemporary Issues in Management Accounting211377 Words   |  846 Pagescontrol systems, Simons (1990: 142) concludes his inXuential ar ticle by noting: We need in fact a better language to describe management control processes. Control systems are used for multiple purposes: Monitoring, learning, signalling, constraint, surveillance, motivation, and others. Yet we use a single descriptor—management control systems—to describe these distinctly diVerent processes. In his subsequent writings on levers of control (Simons 1995), he argued against the traditional opposition ofRead MoreLibrary Management204752 Words   |  820 Pagesbeing taken for granted 5. Promote an undated image 6. Visibility 7. Valuable community resource 8. Rising expectations 9. Survival 10. Beneficial to library image Source: â€Å"Library and Information Services Marketing† (September 2003), compiled and annotated by Marianne Steadley at the University of Illinois Graduate School of Library and Information Science and the University of Illinois Libraries, UI Current LIS Clips, Marketing Information Services 123 2. On a benign level, libraries, â€Å"like

Manual Website Constructor Free Essays

The search box allows finding certain web-pages by determining the search domain (search In the language version set or In all the versions). Search box Search parameters 4. Main menu The main menu consists of five points: Web-pages. We will write a custom essay sample on Manual Website Constructor or any similar topic only for you Order Now Use this point for editing and removing the web-pages of the affiliate website. Add Page. In this section you can create a new web-page, fill it with certain content in the easily understandable panel (the panel enables you to add links, handle the text, upload images etc. ). You can also include the following metabolism for a new web-page: title, keywords, description. Edit Menu. In this section the structure of the website menu can be altered. It serves to add/tilted/remove the menu points. Manage Templates. This section allows managing the website templates (the part of the website page comprising side and bottom menu as well as headings). Furthermore, here you can add/remove links to/ trot the side menu on boot sides trot the text and also change Copyright Design. With the help of this section you can choose any scheme elaborated by our team and change the font. 4. 1 Web-pages For a web-page to be reflected in a certain language, it is necessary to select the language. 4. 1. Remove web-page In order to delete a web-page, please press the button. 4. 1. 2 Edit Page 4. 1. 2. 1 Edit web-page content In order to move to a page editing mode, you need to click the corresponding button. Once you did it, you will see the window of web-page editing. Editing a page is facilitated by the editing tools. Remove the content Save Page layout templates Preview Crop Paste as plain text Copy Paste Paste from Word Print Full text search Undo Redo Insert Checkbook Insert Irradiation Insert text field Insert Select Insert Image Button Insert hidden field Replace text Remove format Mark all Insert form Spell check Insert Text area Insert button Page break Insert symbol Insert SMS e Bold Italics Underline Crossed font Subscript Superscript Billeted list Increase space Decrease space Quotation marks Centered Left-justified liquefied Insert link Insert image Insert flash Insert table Insert horizontal line Show blocks Scale editing window up/down Right-justified Remove link Insert anchor Text color Fill color Numbered list Text style Text format Diva container Font Font size 4. 1. 2. Edit metadata While editing a web-page, metadata (title, keywords, description) can be input. Press the Modify button to save the changes you made. 4. 2 Add Page This window contains the abovementioned panel of editing a page, the field for entering the file name and that for choosing its language version. 4. 3 Edit Menu In this section you need to choose a language version of the menu being edited. 4. 3. 1 Add new element 1) Choose the section tot the menu which you mean to ad ad link to 2) Choose the pr eferred level of the link. ) Enter the name of the link (not less than 3 symbols). 4) Enter the link (Latin letters only). 5) Press the Add button to include the new link to the menu. 4. 3. 2 Edit/remove element In order to delete a certain element, you need to press the Remove button. For editing a menu element after all the necessary modifications were made to the corresponding fields of the element (name and link) press the Change button. 4. 4 Manage Templates The menu of the section consists of three points: 4. 4. Add Link With the help of this section you can add a link in the left or right menu of the main website template. 4. 4. 2 Delete Link In order to remove a link from the main template you need to choose the template field (left or right menu), templates in which you would like to make removal and then Reese the Show links button. After you took all the above-mentioned steps there will appear a list of links of the templates chosen. For removing a certain link, please ti ck the checkbook corresponding to this particular link and press the Delete links from Main Templates 4. . 3 Change Copyright Changing Copyright requires choosing template(s) from the list, entering a new one in the corresponding slot and clicking the Change Copyright button. 4. 5 Design The menu of this section comprises two points: 4. 5. 1 Edit default design In order to change the website design one of the provided templates is to be chosen ND appropriate button to be clicked. You can zoom the design patterns to have a more thorough look on them by clicking on the corresponding image. List the zoomed patterns by clicking the arrow appearing at moving the mouse pointer in the lower right/left corner of the screen. 452 Edit detail ton In this section you can change default font and its size. To do it, choose the corresponding values and click the Edit default font button. 5. FAQ 5. 1 How to place an image? In order to place an image on a web-page, you need to visit the Web-pages section, choose a preferred language and start editing the page (see Edit web-page content section). Place the mouse pointer in the area where you would like to insert an image. Find the Insert image option on the toolbar of web-page editing. You can either upload it or enter a link to it. In order to place an image using the link, visit the Image info section. Enter the link to the image In the URL field, you can also input the text which will be displayed in case of the image being unavailable in the Alternative Text slot. The image will be shown in the Preview field. You can also set the following image parameters: Width Height Boded – framing of he image (1 Hospice – horizontal spacing Peace – vertical spacing Align Click the k button to place an image. In order to upload an image from your computer, please visit the Upload section, press the Browse button, choose the image to be uploaded and press the Send it to the Server button. Once the image is uploaded to the server, the Image Info section will open. Press the k button. 5. 2 How to place a link? In order to place a link on a certain website page, please visit the Web-pages section. Choose the preferred language and pass over to editing it (see Edit page content). Place the mouse pointer in the area where you would like to place a link. Choose Insert link option on the toolbar. Choose a link type in the Link type field. URL – a link to the Internet source Link to the anchor in the text – a link within the weapon E- Mail – a link to the email Choose a link protocol in the Protocol field, enter the link in the URL slot – press the k button to place it. 5. 3 How to place an image with a link? In order to place an image with a link on a certain website page, follow the steps represented in point 5. 1 before pressing the k button. Visit the Link section and enter the link to the URL field; you can choose the method of opening the link in the Target field. How to cite Manual Website Constructor, Papers

Hamlets words Essay Example For Students

Hamlets words Essay It is in doing just this that he meets his very ironic death- upon hearing that Gertrude is distressed, he makes a move from behind the arras and is killed by Hamlet, who thinks that he is Claudius. I think, therefore, that it can be concluded that although Polonius is perhaps immoral, and, to use Hamlets words: an officious fool, he is not a completely corrupt character. However, he is corrupted in his desire to please the king, and so it is clear to the reader that Claudius is one again inextricably linked with the idea of corruption. Gertrude is another character who becomes a victim of Claudius influence. Although she does not take any direct action that would make her seem corrupt, there are a few examples in the play that suggests that she may not be as innocent as she would like people to think. When Hamlet tells her that he knows of Claudius murder, she replies by saying: As kill a King? This lets the reader know that she is puzzled, however it can be seen as ambiguous: either she did not know that Claudius had killed Old Hamlet, or she did not know that Hamlet knew that Claudius had murdered his father. The only explanation for Gertrudes protection of Claudius secret is that she genuinely loves him, although it is unclear whether he loves her in return or if he is just using her. However it is from the language of Hamlet that the reader is given the greatest indication of corruption: but to live in the rank sweat of an enseami d bed, stewed in corruption. Here the use of some very graphic and vile language, such as the words rank and enseamid, by Hamlet one more links Claudius to the idea if disease and decay and shows that Hamlet feels that his mother has been in some way infected or corrupted by Claudius, emphasised by the use of the phrase stewed in corruption. Hamlet shows his distrust of Claudius again, this time warning his mother about becoming part of his corruption: do not spread the compost on the wheels To make them ranker Shakespeares word choice of ranker highlights yet again the corruption of Claudius. Furthermore, Hamlets use of the image spread the compost suggests that he is aware that his mother is easily corruptible and that he does not want her to be overcome by his devious nature. It is though the character of Laertes that the reader sees the best example of Claudius manipulation. In Act IV Scene VII, Laertes is incensed by the death of his father. Claudius not only manages to calm him down but actually uses his Laertes anger to his advantage. He tells Laertes that it was Hamlet who killed his father and Laertes makes it clear that he wants to avenge the death: It warms the very sickness in my heart That I shall live and tell him to his teeth Thus didest thou! This makes it clear to Claudius that he can use Laertes to get to Hamlet, with the decay imagery, the very sickness of my heart, again suggesting Claudius corruption. Claudius plans a duel between the two characters in which one of the swords will be unbated. This is a stroke of genius as it allows Claudius to kill Hamlet before he tells everyone of his murder, but he does not have to commit another murder himself. In my opinion, this is the best example of Claudius ability to corrupt other characters. Laertes is certainly reckless and impulsive, but is not himself corrupt. However, Claudius uses his considerable manipulation skills to corrupt him into committing a murder. William Shakespeares Hamlet is a play which is based on the theme of corruption. Although the characters in the play which I have mentioned may not be completely innocent, Shakespeares clever use of characterisation and language makes it clear that the corruption in the play stems from the character of Claudius. .u1449e83bf0e106ef37dc87b5e2ebe1c9 , .u1449e83bf0e106ef37dc87b5e2ebe1c9 .postImageUrl , .u1449e83bf0e106ef37dc87b5e2ebe1c9 .centered-text-area { min-height: 80px; position: relative; } .u1449e83bf0e106ef37dc87b5e2ebe1c9 , .u1449e83bf0e106ef37dc87b5e2ebe1c9:hover , .u1449e83bf0e106ef37dc87b5e2ebe1c9:visited , .u1449e83bf0e106ef37dc87b5e2ebe1c9:active { border:0!important; } .u1449e83bf0e106ef37dc87b5e2ebe1c9 .clearfix:after { content: ""; display: table; clear: both; } .u1449e83bf0e106ef37dc87b5e2ebe1c9 { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .u1449e83bf0e106ef37dc87b5e2ebe1c9:active , .u1449e83bf0e106ef37dc87b5e2ebe1c9:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .u1449e83bf0e106ef37dc87b5e2ebe1c9 .centered-text-area { width: 100%; position: relative ; } .u1449e83bf0e106ef37dc87b5e2ebe1c9 .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .u1449e83bf0e106ef37dc87b5e2ebe1c9 .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .u1449e83bf0e106ef37dc87b5e2ebe1c9 .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .u1449e83bf0e106ef37dc87b5e2ebe1c9:hover .ctaButton { background-color: #34495E!important; } .u1449e83bf0e106ef37dc87b5e2ebe1c9 .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .u1449e83bf0e106ef37dc87b5e2ebe1c9 .u1449e83bf0e106ef37dc87b5e2ebe1c9-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .u1449e83bf0e106ef37dc87b5e2ebe1c9:after { content: ""; display: block; clear: both; } READ: Hamlet - A Comparison to Humanity EssayBy his detailed exploration of the theme, he makes it clear that there are in a sense two types of corrupt characters: firstly there is Claudius who is completely corrupt. Secondly, there are the other characters who all have had an aspect of their personality exploited by Claudius- Polonius eagerness to please, Gertrudes love for him and Laertes impulsiveness, and so can be considered to have been corrupted by him.